Morgan Webb attended UC Berkeley from 1996 to 2000. She developed computer skills in her free time there, and after graduating from college, worked for a dot-com company as a website administrator. After the company went under during the dot-com bubble burst of 2000, her friend Catherine Schwartz got her hired at TechTV in 2001, and Morgan became employed as the associate producer and web researcher for The Screen Savers. Thanks to her self-taught knowledge of computers and technology, in addition to a camera-friendly appearance, she was quickly promoted to an on-screen member of the program where she presented daily in-depth segments dealing with Microsoft Windows and Linux operating systems, and on select occasions hosted The Screen Savers herself. Throughout 2002 and 2003, she also regularly co-hosted TechTV's Call For Help with Chris Pirillo. In April 2003, Webb left The Screen Savers to co-host X-Play with Adam Sessler.
Webb is one of only six TechTV personalities, including Adam Sessler, Sarah Lane, Chi-Lan Lieu, Kevin Rose, and Brendan Moran, to survive the massive layoffs resulting from the May 2004 merger of G4 and TechTV. However, since G4's change of format, only Adam Sessler and Morgan Webb remain with the network.
In August 2005, Webb became a contributing game columnist for FHM, alongside her regular hosting duties on X-Play. Her monthly column was titled "Tips From The Gaming Goddess". Readers were encouraged to email Morgan their video game-related inquiries; she would then answer one question each month. In February 2007, Webb wrote her final column for the magazine that discontinued its U.S. publication in March.
On August 2, 2007 Webb started a daily [Mon - Fri] video blogging initiative, called WebbAlert. These daily videos are 5-6 minutes in length and consist of a recap of popular technology news of the day. On occasion, Webb will forgo her regular news format in favor of focusing an episode on one particular topic of interest. Past examples include a recap of the annual TED Conference, a viral video special showcasing "future 'Darwin Award' winners", and tech-centric "Holiday Buyer's Guides".